The Mathematical Model of Subtractive Hybridization and Its Practical Application
نویسندگان
چکیده
A novel theory of subtractive hybridization including (or based on) the kinetic model of this process was proposed. A computer program modeling the process of subtraction was developed. Basing on the theory, a novel method of subtractive hybridization was proposed allowing routine comparison of genomes and products of genome expression. The method was applied to studies of the genetic mechanisms of embryogenesis, regeneration, cell differentiation and tumor transformation.
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ورودعنوان ژورنال:
- Proceedings. International Conference on Intelligent Systems for Molecular Biology
دوره 4 شماره
صفحات -
تاریخ انتشار 1996